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Research

Cancer Research

Redefining Care

Sometimes, the standard of care is not enough. That’s when Grady research offers hope.

As one of the nation’s elite teaching hospitals, our clinicians are continually involved in research to find better, more effective treatments. We are committed to investigations that will ultimately end the cancer. Physicians, oncologists, surgeons, and other cancer experts from the Winship Cancer Institute at Emory, Emory and Morehouse schools of medicine, and Grady Health System collaborate on research whose mission is to improve cancer treatments, test the effectiveness of new drugs, and transform cancer care.

On any given day, our experts are involved in literally dozens of cancer studies – from clinical trials to laboratory experiments. Grady’s history of research has helped to redefine how physicians worldwide treat cancer, stroke and other diseases. The benefit to patients is clear: They have access to tomorrow’s medicine today, providing options unavailable at many other institutions.

The center earned the Quality Oncology Practice Initiative (QOPI) Certification which is awarded to outpatient hematology-oncology practices that meet the highest, national standards for delivering quality cancer care. Grady is the first public hospital in Georgia to receive this recognition.

 

ASCO QOPI logo

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Clinical Trials

Clinical trials are an important part of our research. While science provides more insight into the causes of cancer, clinical trials help translate this information into better care for cancer patients. Our patients have the opportunity to participate in clinical trials related to cancer prevention, diagnosis, and treatment.

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Breast

Yu/Torres
A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

E Paplomata
A011502: A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive, HER2 Negative Breast Cancer: The ABC Trial

CNS Meningioma

Shelton
Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma

GU (Urology / Prostate)

Dr. Mehmet Bilen
EA8134: International Penile Advanced Cancer Trial (International Rare Cancers Initiative study)

Rivers
A Health IT based Psychoeducational Intervention for African American Prostate Cancer Patients

Dr. Joseph Shelton
RTOG0924: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial

Alemozafar
Ph II Trial of Retroperitoneal Lymph Node Dissection as first-line of Treatment for Testicular Seminoma with Isolated Retroperitoneal Disease

Multi

Rivers
MSM/TU/UAB CCC Partnership Pilot Study: Cancer Care Connect

Rivers
MSM/TU/UAB CCC Partnership Pilot Study: IMPaCT 2.0

 

Myeloma

Dr. Leon Bernal
MMRC060: Phase II Trial of MLN9708, Dexamethasone and Lenalidomide, Randomized with NF-kB2 Truncation. (Proteasome Inhibitor NF-kB2 Rearrangement Driven Trial, PINR)

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BRCA 1 Gene Research

Dr. Veena N. Rao, Morehouse School of Medicine professor and co-director of the Cancer Biology Program in Grady’s OB/GYN Department, has dedicated her research to better understanding the BRCA1 gene and its mutations to improve the early detection and treatment of African American women with breast cancer.

Her research has led to the development of a patented technology, which when combined with BRCA1 DNA-based testing, promises to revolutionize early detection of hereditary triple negative breast cancers (TNBC), foster development of novel targeted therapies, and save countless lives.

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Research at Grady

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Breast

Dr. Uma Krishnamurti

The Breast Satellite Tissue Bank at Emory University (incorporated WCI1665-09 and WCI1679-09)

Bio-Repository/Bio-Banking – Genetics

 

Dr. Sheryl Gabram

Automated Assessment of Limb Volume Utilizing the Xbox Kinect

Cancer Prevention and Control

 

Patel

The Relationship Between the Human Microbiome and Pt. Symptom Experience in Women Undergoing Combined Modality Thepary for Breast Cancer (SPECTRA)

Cancer Prevention and Control

 

Dr. Preeti Subhedar

A011202: A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (Ct1-3 N1) Who Have Positive Sentinel Lymph Node Disease after Neoadjuvant Chemotherapy

Cancer Prevention and Control

 

Dr. Uma Krishnamurti

Acquisiton of diagnostic biospy

Cancer Related Bio-Repository/Bio-Banking

 

Dr. Uma Krishnamurti

Acquisition of metastatic biopsy

Cancer Related Bio-Repository/Bio-Banking

 

Dr. Gabriela Oprea

Isolation of nucleic acids from Formalin-Fixed Paraffin Embedded (FFPE) breast tumor tissue for downstream genomic-based analyses: Towards the individualization of breast cancer treatment

Diagnostic – Cancer Related Bio-Repository/Bio-Banking

 

GI (Gastrointestinal)

Dr. Lisa C. Flowers,

ANCHOR Study: Anal Cancer/HSIL Outcomes Research Study

Prevention

 

GU (Urology / Prostate)

Dr. Joseph Shelton

Advanced Molecular Imaging with anti-3-[18F]FACBC PET-CT to Improve the Selection and Outcomes of Prostate Cancer Patients Receiving Post-prostatectomy Radiotherapy

Diagnostic

 

Liu/Dr. Ashesh Jani

Ultrasound Tissue-Typing for Prostate Cancer Detection

Diagnostic

 

Dr. Viraj Master

Howard Health Literacy Observational Study

QOL/Economics  – Cancer Prevention and Control

 

GYN (Gynecological)

Dr. Joseph Shelton

Gynecologic Cancer, the Vaginal Microbiome, and Patient Symptom Experience

Cancer Prevention and Control

 

Dr. Lisa C. Flowers

Biomolecular Effects of Topical Curcumin in HSIL Cervical Neoplasia

Cancer Prevention and Control

 

Dr. Gabriela Oprea/Dr. Lisa C. Flowers

Biomarkers of Vaginal and Vulvar Cancers

Cancer Related Bio-Repository/Bio-Banking

 

Dr. Gabriela Oprea

Atypical squamous cells of undetermined origin (ASC-US) colposcopic and surgical-pathology follow-up including immunoperoxidase stains for Human Papilloma Virus (HPV) relevant markers in high-risk HPV (HR-HPV) tested and not tested patients.

Diagnostic – Cancer Related Bio-Repository/Bio-Banking

 

Head and Neck

Liu

WCI1858-10: Quantitative Ultrasound Evaluation of Radiation Toxicity in Head and Neck Cancer Radiotherapy

Diagnostic

 

Dr. Gabriela Oprea

HPV and Oropharyngeal Squamous Cell Carcinoma: The Emory Experience

Genetics

 

Lymphoma

Dr. Lisa C. Flowers/Dr. Leon Bernal

MAYO118-01: Lymphoma Molecular Epidemiologic Resource: Clinical and Epidemiological Studies of Lymphoma

Bio-Repository/Bio-Banking – Genetics

 

Dr. Lisa C. Flowers

LEAD (866-2004): Assessing Treatment Outcomes for Patients with Non-Hodgkin’s Lymphoma

Observational

 

Multi

Sica/ Birdsong /Oprea

The Human Tissue Procurement and banking Services (HTPBS) Core Facility of Emory Healthcare System (EHcS) and Emory University

Bio-Repository/Bio-Banking

 

Flenaugh

All in One – Multicenter, Prospectie triAL of ELectromagnetic BronchoscOpic and ElectromagNetic Transthoracic Approaches for the Biopsy of Peripheral Pulmonary Nodules

Diagnostic

 

Flenaugh

Correlation of Tumor Diameter and Volumetric Measurements in Lung Cancer and Prognostic Implication Using Tip-tracked Navigation System

Diagnostic and Staging

 

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If you are interested in performing research at Grady, find out how to begin by visiting our Office of Research Administration.

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