Research
Redefining Care
Sometimes, the standard of care is not enough. That’s when Grady research offers hope.
As one of the nation’s elite teaching hospitals, our clinicians are continually involved in research to find better, more effective treatments. We are committed to investigations that will ultimately end the cancer. Physicians, oncologists, surgeons, and other cancer experts from the Winship Cancer Institute at Emory, Emory and Morehouse schools of medicine, and Grady Health System collaborate on research whose mission is to improve cancer treatments, test the effectiveness of new drugs, and transform cancer care.
On any given day, our experts are involved in literally dozens of cancer studies – from clinical trials to laboratory experiments. Grady’s history of research has helped to redefine how physicians worldwide treat cancer, stroke and other diseases. The benefit to patients is clear: They have access to tomorrow’s medicine today, providing options unavailable at many other institutions.
The center earned the Quality Oncology Practice Initiative (QOPI) Certification which is awarded to outpatient hematology-oncology practices that meet the highest, national standards for delivering quality cancer care. Grady is the first public hospital in Georgia to receive this recognition.
Clinical Trials
Clinical trials are an important part of our research. While science provides more insight into the causes of cancer, clinical trials help translate this information into better care for cancer patients. Our patients have the opportunity to participate in clinical trials related to cancer prevention, diagnosis, and treatment.
Yu/Torres
A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
E Paplomata
A011502: A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive, HER2 Negative Breast Cancer: The ABC Trial
Shelton
Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma
Dr. Mehmet Bilen
EA8134: International Penile Advanced Cancer Trial (International Rare Cancers Initiative study)
Rivers
A Health IT based Psychoeducational Intervention for African American Prostate Cancer Patients
Dr. Joseph Shelton
RTOG0924: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial
Alemozafar
Ph II Trial of Retroperitoneal Lymph Node Dissection as first-line of Treatment for Testicular Seminoma with Isolated Retroperitoneal Disease
Rivers
MSM/TU/UAB CCC Partnership Pilot Study: Cancer Care Connect
Rivers
MSM/TU/UAB CCC Partnership Pilot Study: IMPaCT 2.0
Dr. Leon Bernal
MMRC060: Phase II Trial of MLN9708, Dexamethasone and Lenalidomide, Randomized with NF-kB2 Truncation. (Proteasome Inhibitor NF-kB2 Rearrangement Driven Trial, PINR)
BRCA 1 Gene Research
Dr. Veena N. Rao, Morehouse School of Medicine professor and co-director of the Cancer Biology Program in Grady’s OB/GYN Department, has dedicated her research to better understanding the BRCA1 gene and its mutations to improve the early detection and treatment of African American women with breast cancer.
Her research has led to the development of a patented technology, which when combined with BRCA1 DNA-based testing, promises to revolutionize early detection of hereditary triple negative breast cancers (TNBC), foster development of novel targeted therapies, and save countless lives.
Research at Grady
The Breast Satellite Tissue Bank at Emory University (incorporated WCI1665-09 and WCI1679-09)
Bio-Repository/Bio-Banking – Genetics
Automated Assessment of Limb Volume Utilizing the Xbox Kinect
Cancer Prevention and Control
Patel
The Relationship Between the Human Microbiome and Pt. Symptom Experience in Women Undergoing Combined Modality Thepary for Breast Cancer (SPECTRA)
Cancer Prevention and Control
A011202: A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (Ct1-3 N1) Who Have Positive Sentinel Lymph Node Disease after Neoadjuvant Chemotherapy
Cancer Prevention and Control
Acquisiton of diagnostic biospy
Cancer Related Bio-Repository/Bio-Banking
Acquisition of metastatic biopsy
Cancer Related Bio-Repository/Bio-Banking
Isolation of nucleic acids from Formalin-Fixed Paraffin Embedded (FFPE) breast tumor tissue for downstream genomic-based analyses: Towards the individualization of breast cancer treatment
Diagnostic – Cancer Related Bio-Repository/Bio-Banking
Advanced Molecular Imaging with anti-3-[18F]FACBC PET-CT to Improve the Selection and Outcomes of Prostate Cancer Patients Receiving Post-prostatectomy Radiotherapy
Diagnostic
Liu/Dr. Ashesh Jani
Ultrasound Tissue-Typing for Prostate Cancer Detection
Diagnostic
Howard Health Literacy Observational Study
QOL/Economics – Cancer Prevention and Control
Gynecologic Cancer, the Vaginal Microbiome, and Patient Symptom Experience
Cancer Prevention and Control
Biomolecular Effects of Topical Curcumin in HSIL Cervical Neoplasia
Cancer Prevention and Control
Dr. Gabriela Oprea/Dr. Lisa C. Flowers
Biomarkers of Vaginal and Vulvar Cancers
Cancer Related Bio-Repository/Bio-Banking
Atypical squamous cells of undetermined origin (ASC-US) colposcopic and surgical-pathology follow-up including immunoperoxidase stains for Human Papilloma Virus (HPV) relevant markers in high-risk HPV (HR-HPV) tested and not tested patients.
Diagnostic – Cancer Related Bio-Repository/Bio-Banking
Liu
WCI1858-10: Quantitative Ultrasound Evaluation of Radiation Toxicity in Head and Neck Cancer Radiotherapy
Diagnostic
HPV and Oropharyngeal Squamous Cell Carcinoma: The Emory Experience
Genetics
Dr. Lisa C. Flowers/Dr. Leon Bernal
MAYO118-01: Lymphoma Molecular Epidemiologic Resource: Clinical and Epidemiological Studies of Lymphoma
Bio-Repository/Bio-Banking – Genetics
LEAD (866-2004): Assessing Treatment Outcomes for Patients with Non-Hodgkin’s Lymphoma
Observational
Sica/ Birdsong /Oprea
The Human Tissue Procurement and banking Services (HTPBS) Core Facility of Emory Healthcare System (EHcS) and Emory University
Bio-Repository/Bio-Banking
Flenaugh
All in One – Multicenter, Prospectie triAL of ELectromagnetic BronchoscOpic and ElectromagNetic Transthoracic Approaches for the Biopsy of Peripheral Pulmonary Nodules
Diagnostic
Flenaugh
Correlation of Tumor Diameter and Volumetric Measurements in Lung Cancer and Prognostic Implication Using Tip-tracked Navigation System
Diagnostic and Staging
If you are interested in performing research at Grady, find out how to begin by visiting our Office of Research Administration.