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SICKLE CELL TREATMENT

Leading the way in sickle cell care

Sickle cell disease is a chronic, incurable, genetic disease of the blood and a diagnosis can feel confusing or scary. That’s why Grady is committed to revolutionizing sickle cell care through the Georgia Comprehensive Sickle Cell Center.

OVERVIEW

The nation’s best sickle cell care


The Georgia Comprehensive Sickle Cell Center at Grady is the world’s first 24-hour acute care center for adult sickle cell patients and the only comprehensive sickle cell center in Georgia. Our sickle cell team has both a deep understanding of the symptoms that sickle cell patients face and the full range of problems that can be associated with the disease. We offer:

  • Both primary care by appointment and 24/7 acute care for pain crisis management.
  • Hematologists specializing in sickle cell disease that provide personalized, ongoing care.
  • Experience treating thousands of patients each year for everything from acute pain to blood transfusions and disease-modifying therapies.
  • Support services to help ease the toll sickle cell takes on patients and families, including social work services, sickle cell education, and pediatric transition classes

How do I make an appointment?

You can make an appointment by:

  • Calling (404) 616-1000, Monday-Friday, from 6 a.m. to 11 p.m. to schedule your appointment.
  • Visiting MyChart to request your appointment online if you are an existing Grady patient with a MyChart account.

services

Treatments we offer


We provide the more comprehensive care available for sickle cell disease patients, including:

We provide in-center red blood cell exchange, also known as therapeutic erythrocytapheresis, and transfusion therapy. Erythrocytapheresis is a non-surgical therapy that removes and replaces a patient’s red blood cells. A patient’s blood is removed through a needle or catheter and circulated through a machine that separated red cells, white cells, platelets, and plasma. The red cells responsible for carrying oxygen to all parts of the body are discarded and replaced with donated red blood cells. The donor red blood cells circulate back to the patient with the other blood components (white cells, platelets, and plasma) through a return needle. Transfusion therapy involves regularly administering red blood cells to patients.

Hydroxyurea is a medicine that is used to reduce the frequency of pain and the need for blood transfusions in sickle cell patients. Hydroxyurea works by increasing the level of a special type of hemoglobin called hemoglobin F (HbF), which is more effective in binding and carrying oxygen around the body, reducing anemia symptoms.

We help to manage patient pain using a variety of non-narcotic prescriptions and other therapies.

L-glutamine (ENDARI), Crizanlizumab (ADAKVEO), and Voxelotor (OXBRYTA) are both recently FDA approved therapies for sickle cell disease and are available for consideration for treatment for sickle cell patients at the center.

We use a multi-disciplinary approach to treat these slow-healing wounds.

Primary Location

Grady Memorial Hospital

Phone:

(404) 616-1000

Location:

80 Jesse Hill Jr Dr SE, Atlanta, GA 30303

Location Details
See all locations

CONDITIONS TREATED

What issues associated with sickle cell do we treat?

Sickle cell disease is common and can affect many people. We routinely care for the illnesses most common issues, including:


Fatigue and anemia

Sickle cell anemia is a condition in which there aren’t enough healthy red blood cells to carry oxygen adequately throughout your body. The red blood cells are shaped like sickles or crescent moons. This anemic condition typically results in fatigue.

Infections

People with sickle cell disease have an increased risk of developing certain infections, including pneumonia, bloodstream infections, meningitis, and bone infections, because sickle cells affect the spleen, leading to damage and poor protection against infection. We administer immunizations to help protect against infections.

Kidney disease

Sickle cell patients can be affected by developing kidney disease. We have a multidisciplinary approach and have kidney specialists in the outpatient clinic to care for this complication.

Leg ulcers

Sickle cell patients commonly develop leg ulcers requiring intense wound care to reduce the pain and heal the lesion.

Stroke and acute chest syndrome

Sickle cell patients may be at risk of stroke and acute chest syndrome. We reduce the risk by getting patients on chronic transfusions and disease-modifying treatments such as hydroxyurea.

Doctors

Our doctors


Grady is staffed by the nation’s top physicians. We bring the best medical care to Atlanta, with nationally recognized physicians, leading-edge technology, and world-class facilities.

LOCATIONS

Sickle Cell Center Center Locations and Directions


Grady Memorial Hospital

Phone:

(404) 616-1000 (Main)
(404) 616-1000 (Appointments)

Location:

80 Jesse Hill Jr Drive SE
Atlanta, GA 30303
Ground Floor

Location Details

Grady Memorial Hospital

Phone:

(404) 616-1000 (Main)
(404) 616-1000 (Appointments)

Location:

80 Jesse Hill Jr Drive SE
Atlanta, GA 30303
Ground Floor

Location Details

RESEARCH

Sickle cell research at Grady


Research conducted at Grady is helping to redefine the way doctors around the world treat sickle cell. As one of the nation’s elite teaching hospitals, our clinicians are driven to explore finding better and more effective ways to care for sickle cell patients.