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Gregory Martin, MD, MSc, FACP, FCCP, FCCM, ATSF

Gregory S. Martin, MD, MSc, FACP, FCCP, FCCM, ATSF

Chair of Critical Care

Greg S. Martin, M.D., M.Sc. is Professor of Medicine at Emory University in the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, where he is the Executive Associate Division Director. Dr. Martin completed his undergraduate studies at Duke University; medical school, residency and subspecialty fellowship training were completed at Vanderbilt University and a post-graduate Master of Science degree at Emory University. Dr. Martin serves as the Research Director for the Emory Critical Care Center (ECCC), Director of the Emory/Georgia Tech Predictive Health Institute and the affiliated Center for Health Discovery and Well Being, and the Director of the multi-institutional Clinical Research Centers within the NIH-funded Georgia Clinical and Translational Science Alliance (Georgia CTSA). At Grady Memorial Hospital, Dr. Martin serves as the chair of the Critical Care Committee.
Dr. Martin’s conducts clinical research in critically ill patients, particularly in sepsis and acute respiratory distress syndrome (ARDS), spanning epidemiology and health services research through biomarker studies to randomized trials of new treatments. Dr. Martin’s clinical trials studying fluid balance in ARDS led to definitive trials conducted by the ARDS Network and set the foundation for clinical care. His health services research in sepsis produced the first national scale longitudinal study of sepsis, demonstrating secular trends in the incidence and outcome, and important healthcare disparities.
Dr. Martin is a member of several professional societies and serves on the board of directors for the Society of Critical Care Medicine, where he will serve as President in 2021. Of his many awards and honors, Dr. Martin received the Golden Apple teaching award from Emory University.

Specialties

  • Pulmonary Disease
  • Critical Care Medicine

Board Certifications

  • ABMS Internal Medicine

Fellowships

  • Vanderbilt University Medical Center

Affiliations

  • Emory

Education & Training

  • Medical School: Vanderbilt University College of Medicine
  • Internship: Vanderbilt University Medical Center
  • Residency: Vanderbilt University Medical Center

Honors & Awards

Selected for fellowship in several societies (ACP, ACCP, SCCM, ATS)

Twice recognized by Emory University as having published papers cited >1000 times ("MilliPub Club")

Honorary designation as Master Clinician from the Emory University Department of Medicine

Recipient of the Golden Stethoscope Award from Emory Healthcare

Recipient of the "Pulmonary Star” Award from the Emory Division of Pulmonary, Allergy, Critical Care and Sleep Medicine

Selected member of Faculty of 1000 in Medicine, Section on Critical Care and Emergency Medicine

Publications

https://bit.ly/gsmartin_NCBI

Billington ME, Seethala RR, Hou PC, Takhar SS, Askari R, Aisiku IP; USIITG-CIOS investigators. Differences in prevalence of ICU protocols between neurologic and non-neurologic patient populations. J Crit Care 2019; 52: 63-67.

Hager DN, Hooper MH, Bernard GR, Busse LW, Ely EW, Fowler AB, Gaieski DF, Hall A, Hinson JS, Jackson JC, Kelen GD, Levine M, Lindsell CJ, Malone RE, McGlothlin A, Rothman RE, Viele K, Wright DW, Sevransky JE, Martin GS. The Vitamin C, Thiamine, and Steroids in patients with Sepsis (VICTAS) Protocol: A prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial. TRIALS 2019; In Press.

Kempker JA, Kramer MR, Waller LA, Wang HE, Martin GS. State-level hospital compliance with and performance in the Centers for Medicaid & Medicare Services’ Early Management Severe Sepsis and Septic Shock Bundle. Crit Care 2019; 23: 92.

Lopansri BK, Miller RR, Burke JP, Levy M, Opal S, Rothman RE, D’Alessio FR, Sidhaye VK, Balk R, Greenberg JA, Yoder M, Patel GP, Gilbert E, Afshar M, Parada JP, Martin GS, Esper AM, Kempker JA, Narasimhan M, Tsegaye A, Hahn S, Mayo P, McHugh L, Rapisarda A, Sampson D, Brandon RA, Seldon TA, Yager TD, Brandon RB. Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort. J Intensive Care 2019; 7: 13.

Hotchkiss RS, Colston E, Yende S, Angus DC, Moldawer LL, Crouser ED, Martin GS, Coopersmith CM, Brakenridge S, Mayr FB, Park PK, Ye J, Catlett IM, Girgis IG, Grasela DM. Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Anti-programmed Cell Death-Ligand 1 (BMS-936559). Crit Care Med 2019; in press. doi: 10.1097/CCM.0000000000003685

Rhee C, Jentzsch MS, Kadri SS, Seymour CW, Angus DC, Murphy DJ, Martin GS, Dantes RB, Epstein L, Fiore AE, Jernigan JA, Danner RL, Warren DK, Septimus EJ, Hickok J, Poland RE, Jin R, Fram D, Schaaf R, Wang R, Klompas M; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons. Crit Care Med 2018 Nov 13; in press. doi: 10.1097/CCM.0000000000003554

Rhee C, Zhang Z, Kadri SS, Murphy DJ, Martin GS, Overton E, Seymour CW, Angus DC, Dantes R, Epstein L, Fram D, Schaaf R, Wang R, Klompas M; CDC Prevention Epicenters Program. Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria. Crit Care Med 2019; 47(3): 307-314.

Martin GS, Bassett P. Crystalloids vs. colloids for fluid resuscitation in the Intensive Care Unit: A systematic review and meta-analysis. J Crit Care 2018; 50:144-154.

Kempker JA, Kramer MR, Waller LA, Martin GS. Risk Factors for Septicemia Deaths and Disparities in a Longitudinal US Cohort. Open Forum Infect Dis 2018; 5(12): ofy305. https://doi.org/10.1093/ofid/ofy305

Miller III RR, Lopansri BK, Burke JP, Levy M, Opal S, Rothman RE, D'Alessio FR, Sidhaye VK, Aggarwal NR, Balk R, Greenberg JA, Yoder M, Patel G, Gilbert E, Afshar M, Parada JP, Martin GS, Esper AM, Kempker JA, Narasimhan M, Tsegaye A, Hahn S, Mayo P, van der Poll T, Schultz MJ, Scicluna BP, Klein Klouwenberg P, Rapisarda A, Seldon TA, McHugh LC, Yager TD, Cermelli S, Sampson D, Rothwell V, Newman R, Bhide S, Kirk JT, Navalkar K, Davis RF, Brandon RA, Brandon RB. Validation of a Host Response Assay, Septicyte LAB, for Discriminating Sepsis from SIRS in the ICU. Am J Respir Crit Care Med. 2018; 198(7):903-913.

Smith EM, Jones JL, Han JE, Alvarez JA, Sloan JH, Konrad RJ, Zughaier SM, Martin GS, Ziegler TR, Tangpricha V. High-Dose Vitamin D3 Administration Is Associated With Increases in Hemoglobin Concentrations in Mechanically Ventilated Critically Ill Adults: A Pilot Double-Blind, Randomized, Placebo-Controlled Trial. JPEN J Parenter Enteral Nutr; 2018; 42(1): 87-94.

Ike JD, Kempker JA, Kramer MR, Martin GS. The Association Between Acute Respiratory Distress Syndrome Hospital Case Volume and Mortality in a U.S. Cohort, 2002-2011. Crit Care Med. 2018; 46(5):764-773.

Topel ML, Shen J, Morris AA, Al Mheid I, Sher S, Dunbar SB, Vaccarino V, Sperling LS, Gibbons GH, Martin GS, Quyyumi AA. Comparisons of the Framingham and Pooled Cohort Equation Risk Scores for Detecting Subclinical Vascular Disease in Blacks Versus Whites. Am J Cardiol 2017; 121(5): 564-569.

Han JE, Alvarez JA, Staitieh B, Tangpricha V, Hao L, Ziegler TR, Martin GS, Brown LAS. Oxidative stress in critically ill ventilated adults: effects of vitamin D3 and associations with alveolar macrophage function. Eur J Clin Nutr 2017; 72(5):744-751.

Topel ML, Hayek SS, Ko YA, Sandesara PB, Samman Tahhan A, Hesaroieh I, Mahar E, Martin GS, Waller EK, Quyyumi AA. Sex Differences in Circulating Progenitor Cells. J Am Heart Assoc 2017; 6(10). pii: e006245.

Kelli HM, Corrigan FE, Heinl RE, Dhindsa DS, Hammadah M, Samman-Tahhan A, Sandesara P, O'Neal WT, Al Mheid I, Ko Y-A, Vaccarino V, Ziegler TR, Sperling LS, Brigham K, Jones P, Martin GS, Quyyumi AA. Relation of Changes in Body Fat Distribution to Oxidative Stress. Am J Cardiol 2017; 120(12):2289-2293.

Corrigan FE 3rd, Kelli HM, Dhindsa DS, Heinl RE, Al Mheid I, Hammadah M, Hayek SS, Sher S, Eapen DJ, Martin GS, Quyyumi AA. Changes in truncal obesity and fat distribution predict arterial health. J Clin Lipidol 2017; pii: S1933-2874(17)30418-X.

Holder AL, Overton E, Lyu P, Kempker JA, Nemati S, Razmi F, Martin GS, Buchman TG, Murphy DJ. Serial Daily Organ Failure Assessment Beyond ICU Day 5 Does Not Independently Add Precision to ICU Risk-of-Death Prediction. Crit Care Med 2017; 45(12):2014-2022.

Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, Dakri SS, Angus DC, Danner FL, Fiore AE, Jernigan JA, Martin GS, Septimus E, Warren DK, Karcz A, Chan C, Menchaca JT, Wang R, Gruber S, Klompas M, CDC Prevention Epicenter Program. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA 2017; 318(13): 1241-1249.

Kelli HM, Hammadah M, Amhed H, Ko Y-A, Topel M, Samman-Tahhan A, Awad M, Patel K, Mohammed K, Sperling LS, Pemu P, Vaccarino V, Lewis T, Taylor H, Martin G, Gibbons GH, Quyyumi AA. Association Between Living in Food Deserts and Cardiovascular Risk. Circulation: Cardiovascular Quality and Outcomes 2017;10:e003532

Chen CW, Mittal R, Klingensmith NJ, Burd EM, Terhorst C, Martin GS, Coopersmith CM, Ford ML. Cutting Edge: 2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis. J Immunol 2017; 199(6): 1961-1966.

Liao TV, Rabinovich M, Abraham P, Perez S, DiPlotti C, Han JE, Martin GS, Honig E. Evaluation of medication errors with implementation of electronic health record technology in the medical intensive care unit. Open Access J Clin Trials 2017; 9: 31-40.

Zhu Z, Wang T, Liu Z, Yi L, Yang Z, Bian W, Chen W, Wang S, Li G, Li A, Martin GS, Zhu X. Plasma Neutrophil Elastase and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome: A Multicenter Survival and Longitudinal Prospective Observation Study. Shock 2017; 48(2): 168-174.

Polito CC, Bloom I, Yancey AH, Lairet JR, Isakov AP, Martin GS, Rajasekar S, Patel A, Murphy DJ, Sevransky JE. Prehospital sepsis care: Understanding provider knowledge, behaviors, and attitudes. Am J Emerg Med 2017; 35(2): 362-365.

Smith EM, Jones JL, Han JE, Alvarez JA, Sloan JH, Konrad RJ, Zughaier SM, Martin GS, Ziegler TR, Tangpricha V. High-Dose Vitamin D3 Administration Is Associated With Increases in Hemoglobin Concentrations in Mechanically Ventilated Critically Ill Adults: A Pilot Double-Blind, Randomized, Placebo-Controlled Trial. J Parenter Enteral Nutr 2018 Jan;42(1):87-94. doi: 10.1177/0148607116678197.

Seitz KP, Sevransky JE, Martin GS, Roback JD, Murphy DJ. Evaluation of RBC Transfusion Practice in Adult ICUs and the Effect of Restrictive Transfusion Protocols on Routine Care. Crit Care Med 2017; 45(2):271-281.

Al Mheid I, Kelli HM, Ko YA, Hammadah M, Ahmed H, Hayek S, Vaccarino V, Ziegler TR, Gibson G, Lampl M, Alexander RW, Brigham K, Martin GS, Quyyumi AA. Effects of a Health-Partner Intervention on Cardiovascular Risk. J Am Heart Assoc 2016; 5(10). pii: e004217.

Cochi SE, Kempker JA, Annangi S, Kramer MR, Martin GS. Mortality Trends of Acute Respiratory Distress Syndrome in the United States from 1999-2013. Ann Am Thorac Soc 2016; 13(10): 1742-1751.

Al Mheid I, Hayek SS, Ko YA, Akbik F, Li Q, Ghasemzadeh N, Martin GS, Long Q, Hammadah M, Maziar Zafari A, Vaccarino V, Waller EK, Quyyumi AA. Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors. Circ Res 2016; 119(7): 801-9.

Han JE, Rabinovich M, Abraham P, Satyanarayana P, Liao TV, Udoji TN, Cotsonis GA, Honig EG, Martin GS. Effect of Electronic Health Record Implementation in Critical Care on Survival and Medication Errors. Am J Med Sci 2016; 351(6): 576-81.

Han JE, Jones JL, Tangpricha V, Brown MA, Brown LS, Hao L, Hebbar G, Lee MJ, Liu S, Ziegler TR, Martin GS. High dose vitamin D administration in ventilated intensive care unit patients: A pilot double blind randomized control trial. J Clin Translat Endocrin 2016; 4: 59-65.

Kempker JA, Magee MJ, Cegielski JP, Martin GS. Associations Between Vitamin D Level and Hospitalizations With and Without an Infection in a National Cohort of Medicare Beneficiaries Am J Epidemiol 2016; 183(10): 920-9.

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016; 315(8): 801-810.

Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD, Singer M; Sepsis Definitions Task Force. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016; 315(8): 775-787.

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, Deutschman CS, Escobar GJ, Angus DC. Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016; 315(8): 762-774.

Seymour CW, Coopersmith CM, Deutschman CS, Gesten F, Klompas M, Levy M, Martin GS, Osborn TM, Rhee C, Warren DK, Watson RS, Angus DC. Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria. Crit Care Med 2016; 44(3): e122-e130.

Angus DC, Seymour CW, Coopersmith CM, Deutschman CS, Klompas M, Levy MM, Martin GS, Osborn TM, Rhee C, Watson RS. A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria. Crit Care Med 2016; 44(3): e113-e121.

Feingold P, Mina MJ, Burke RM, Hashimoto B, Gregg S, Martin GS, Leeper K, Buchman T, Long-Term Survival Following In-Hospital Cardiac Arrest: A matched cohort study. Resuscitation 2016; 99: 72–78.

Hajjar I, Goldstein FC, Martin GS, Quyyumi A. Roles of Arterial Stiffness and Blood Pressure in Hypertension-Associated Cognitive Decline in Healthy Adults. Hypertension 2016; 67(1): 171-5.

Al Mheid I, Held E, Uphoff I, Martin GS, Dunbar S, Bidulescu A, Gibbons G, Jones DP, Vaccarino V, Quyyumi AA. Depressive Symptoms and Subclinical Vascular Disease: The Role of Regular Physical Activity. J Am Coll Cardiol 2016; 67(2): 232-4.

Ziegler TR, May AK, Hebbar G, Easley KA, Griffith DP, Dave N, Collier BR, Cotsonis GA, Hao L, Leong T, et al. Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial. Ann Surg 2016; 263(4): 646-55.

Murphy DJ, Lyu PF, Gregg SR, Martin GS, Hockenberry JM, Coopersmith CM, Sterling M, Buchman TG, Sevransky J. Using Incentives to Improve Resource Utilization: A Quasi-Experimental Evaluation of an ICU Quality Improvement Program. Crit Care Med 2016; 44(1): 162-170.

Johnston KJ, Hockenberry JM, Rask KJ, Cunningham L, Brigham KL, Martin GS. Health Care Expenditures for University and Academic Medical Center Employees Enrolled in a Pilot Workplace Health Partner Intervention. J Occup Environ Med 2015; 57(8): 897-903.

Sevransky JE, Checkley W, Herrera P, Pickering BW, Barr J, Brown SM, Chang SY, Chong D, Kaufman D, Fremont RD, Girard TD, Hoag J, Johnson SB, Kerlin MP, Liebler J, O'Brien J, O'Keefe T, Park PK, Pastores SM, Patil N, Pietropaoli AP, Putman M, Rice TW, Rotello L, Siner J, Sajid S, Murphy DJ, Martin GS; United States Critical Illness and Injury Trials Group-Critical Illness Outcomes Study Investigators. Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Crit Care Med 2015; 43(10):2076-84.

Corrigan FE 3rd, Al Mheid I, Eapen DJ, Hayek SS, Sher S, Martin GS, Quyyumi AA. Low testosterone in men predicts impaired arterial elasticity and microvascular function. Int J Cardiol 2015; 194: 94-9.

Polito CC, Isakov A, Yancey AH 2nd, Wilson DK, Anderson BA, Bloom I, Martin GS, Sevransky JE. Prehospital recognition of severe sepsis: development and validation of a novel emergency medical services screening tool. Am J Emerg Med 2015; 33(9):1119-25.

Smith EM, Alvarez JA, Martin GS, Zughaier SM, Ziegler TR, Tangpricha V. Vitamin D deficiency is associated with anaemia among African Americans in a US cohort. Br J Nutr 2015; 113: 1732-1740.

Cribbs SK, Tse C, Andrews J, Shenvi N, Martin GS. Characteristics and Outcomes of HIV-Infected Patients With Severe Sepsis: Continued Risk in the Post-Highly Active Antiretroviral Therapy Era. Crit Care Med 2015; 43(8): 1638-45.

Kempker JA, West KG, Kempker RR, Siwamogsatham O, Alvarez JA, Tangpricha V, Ziegler TR, Martin GS. Vitamin D status and the risk for hospital-acquired infections in critically ill adults: a prospective cohort study. PLoS One. 2015; 10(4):e0122136.

Nirappil F, Maheshwari A, Andrews J, Martin GS, Esper AM, Cribbs SK. Characteristics and Outcomes of HIV-1-infected Patients with Acute Respiratory Distress Syndrome. J Crit Care 2015 Feb; 30(1): 60-4.

Tabassum R, Cunningham L, Stephens EH, Sturdivant K, Martin GS, Brigham KL, Gibson G. A Longitudinal Study of Health Improvement in the Atlanta CHDWB Wellness Cohort. J Pers Med 2014; 4(4): 489-507.

Kempker JA, Honig EG, Martin GS. Effects of Marijuana Exposure on Expiratory Airflow: A Study of Adults who Participated in the U.S. National Health and Nutrition Examination Study. Ann Am Thorac Soc 2015; 12(2):135-41.

Han JE, Trammell AR, Finklea JD, Udoji TN, Dressler DD, Honig EG, Abraham P, Ander DS, Cotsonis GA, Martin GS, Schulman DA. Evaluating Simulation-Based ACLS Education on Patient Outcomes: A Randomized, Controlled Pilot Study. J Grad Med Educ 2014; 6(3): 501-6.

Prebil SE, Andrews J, Cribbs SK, Martin GS, Esper AM. Safety of Bronchoscopy in Critically Ill Patients. J Crit Care 2014; 29(6): 961-4.

Wilson DK, Polito CC, Haber MJ, Yancey A 2nd, Martin GS, Isakov A, Anderson BJ, Kundel V, Sevransky JE. Patient factors associated with identification of sepsis in the ED. Am J Emerg Med 2014; 32(10): 1280-1.

Al Mheid I, Veledar E, Martin GS, Vaccarino V, Quyyumi AA. Functional health and well-being, arterial stiffness and vascular dysfunction in healthy adults. Int J Cardiol 2014; 174(3):729-30.

Pastores SM, Martin GS, Baumann MH, Curtis JR, Farmer JC, Fessler HE, Gupta R, Hill NS, Hyzy RC, Kvetan V, Macgregor DA, O'Grady NP, Ognibene FP, Rubenfeld GD, Sessler CN, Siegal E, Simpson SQ, Spevetz A, Ward NS, Zimmerman JL; Prepared by: CCSC Task Force on Critical Care Educational Pathways in Internal Medicine; Task Force Members. Training Internists to Meet Critical Care Needs in the United States: A Consensus Statement from the Critical Care Societies Collaborative (CCSC). Crit Care Med 2014; 42(5): 1272-1279.

Alvarez J, Chowdhury R, Jones DP, Martin GS, Brigham KL, Binongo JN, Ziegler TR, Tangpricha V. Vitamin D status is independently associated with plasma glutathione and cysteine thiol/disulfide redox status in adults. Clin Endocrin 2014; 81(3): 458-466.

Farrugia A, Bansal M, Balboni S, Kimber MC, Martin GS, Cassar J. Choice of Fluids in Severe Septic Patients - a Cost-Effectiveness Analysis Informed by Recent Clinical Trials. Rev Recent Clin Trials 2014; 9(1): 21-30.

Cribbs SK, Park Y, Guidot DM, Martin GS, Brown LA, Lennox J, Jones DP. Metabolomics of Bronchoalveolar Lavage Differentiate Healthy HIV-1-Infected Subjects from Controls. AIDS Res Hum Retroviruses 2014; 30(6): 579-585.

Cribbs SK, Martin GS, Brown LA, Lennox JL, Guidot DM. Anti-retroviral Therapy is Associated with Decreased Alveolar Glutathione Levels even in Healthy HIV-infected Individuals. PLOS One 2014; 9(2): e88630.

Polito CC, Cribbs SK, Martin GS, O'Keeffe T, Herr D, Rice TW, Sevransky JE. Navigating the Institutional Review Board Approval Process in a Multicenter Observational Critical Care Study. Crit Care Med 2014; 42(5): 1105-9.

Checkley W, Martin GS, Brown SM, Chang SY, Dabbagh O, Fremont RF, Girard TD, Rice TW, Howell MD, Johnson SB, O’Brien J, Park PK, Pastores SM, Patil NT, Pietropaoli AP, Putman M, Rotello L, Siner J, Sajid S, Murphy DM, Sevransky SE, for the USCIITG-CIOS Investigators. Structure, process and annual intensive care unit mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study (USCIITG-CIOS). Crit Care Med 2014; 42(2): 344-356.

Bansal M, Farrugia A, Balboni S, Martin G. Relative survival benefit and morbidity with fluids in severe sepsis - a network meta-analysis of alternative therapies. Curr Drug Saf 2013;8(4): 236-45.

Park Y, Lee K, Ziegler TR, Martin GS, Hebbar G, Vidakovic B, Jones DP. Multifractal analysis for nutritional assessment. PLoS One 2013; 8(8): e69000.

Lemos-Filho LB, Mikkelsen ME, Martin GS, Dabbagh O, Adesanya A, Gentile N, Esper A, Gajic O, Gong MN, USCIITG-LIPS Investigators. Sex, Race, and the Development of Acute Lung Injury. Chest 2013; 143(4): 901-909.

Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. Whole Genome Sequencing in support of Wellness and Health Maintenance. Genome Med 2013; 5(6): 58.

Karnatovskaia LV, Festic E, Gajic O, Carter RE, Lee AS, Ahmed A, Gajic O, Malinchoc M, Kor DJ, Afessa B, Cartin-Ceba R, Dabbagh O, Nagam N, Patel S, Karo A, Hess B, Park PK, Harris J, Napolitano L, Raghavendran K, Hyzy RC, Blum J, Dean C, Adesanya A, Hosur S, Enoh V, Chang SY, Patrawalla A, Elie M, Hou PC, Barry JM, Shempp I, Malhotra A, Frendl GY, Anderson H, Tchorz K, McCarthy MC, Uddin D, Hoth JJ, Yoza B, Mikkelsen M, Christie JD, Gaieski DF, Lanken P, Meyer N, Shah C, Gentile NT, Stevenson K, Freeman B, Srinivasan S, Gong MN, Talmor D, Bender SP, Garcia M, Bajwa E, Malhotra A, Thompson BT, Christiani DC, Watkins TR, Deem S, Treggiari M, Festic E, Lee A, Daniels J, Cengiz M, Yilmaz M, Iscimen R, Kaufman D, Esper A, Martin G, Sadikot R, Douglas I, Sevransky J. Prehospital amiodarone may increase the incidence of acute respiratory distress syndrome among patients at risk. J Crit Care 2012; 27(5): 447-453.

Cordemans C, De Iaet I, Van Regenmortel N, Schoonheydt K, Dits H, Martin G, Huber W, Malbrain MLNG. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment. Ann Intensive Care 2012; 2(Suppl 1): S15.

Cribbs SK, Sutcliffe DJ, Taylor WR, Rojas M, Easley KA, Tang L, Brigham KL, Martin GS. Circulating endothelial progenitor cells inversely associate with organ dysfunction in sepsis. Intensive Care Med 2012; 38(3): 429-36.

Rahbar AJ, Rabinovich M, Abraham P, Honig EG, Martin GS. Outcomes after administration of drotrecogin alfa in patients with severe sepsis at an urban teaching hospital. J Med Res Sci 2012; 2(1): 7-12.

Cooke CR, Erickson SE, Eisner MD, Martin GS. Trends in the incidence of non-cardiogenic acute respiratory failure: the role of race. Crit Care Med 2012; 40(5): 1532-8.

Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC. A randomized trial of recombinant human granulocyte-macrophage colony-stimulating factor for patients with acute lung injury. Crit Care Med 2012; 40(1): 90-97.

Greenberg JA, Lennox J, Martin GS. Outcomes for Critically Ill Patients with HIV and Severe Sepsis in the Era of Highly Active Antiretroviral Therapy. J Crit Care 2012; 27(1): 51-7.

Han SH, Martin GS, Maloney JP, Shanholtz C, Barnes KC, Murray S, Sevransky JE. Short women with severe sepsis-related acute lung injury receive lung protective ventilation less frequently: an observational cohort study. Crit Care 2011; 15(6): R262. (doi:10.1186/cc10524).

Ali NA, Gutteridge D, Shahul S, Checkley W, Sevransky J, Martin GS. Critical illness outcomes study: an observational study of protocols and mortality in intensive care units. Open Access J Clin Trials 2011; 3: 55-65.

Park Y, Jones DP, Ziegler TR, Lee K, Kotha K, Yu T, Martin GS. Metabolic effects of albumin therapy in acute lung injury measured by 1H-NMR spectroscopy of plasma: a pilot study. Crit Care Med 2011; 39(10):2308-13.

Satterwhite L, Mehta A, Martin GS. Novel Findings from the Second Wave of Adult H1N1 Disease in the United States. Crit Care Med 2010; 38(10): 2059-61.

Seymour CW, Iwashyna TJ, Cooke CR, Hough CL, Martin GS. Marital status and the epidemiology and outcomes of sepsis. Chest 2010; 137(6):1289-1296.

Beale R, Janes JM, Brunkhorst FM, Dobb G, Levy MM, Martin GS, Ramsay G, Silva E, Sprung CL, Vallet B, Vincent J, Costigan TM, Leishman AG, Williams MD, Reinhart K. Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry. Crit Care 2010, 14: R102.

Sevransky JE, Martin GS, Shanholtz C, Mendez-Tellez PA, Pronovost P, Brower R, Needham DM. Mortality in sepsis vs. non-sepsis induced acute lung injury. Crit Care 2009;13:R150.

Beale R, Reinhart K, Brunkhorst FM, Dobb G, Levy M, Martin G, Martin C, Ramsey G, Silva E, Vallet B, Vincent J-L, Janes JM, Sarwat S, Williams MD. Promoting Global Research Excellence in Severe Sepsis (PROGRESS): Lessons from an International Sepsis Registry. Infection 2009; 37(3): 222-32.

Berkowitz DM, Danai PA, Eaton S, Moss M, Martin GS. Alcohol Abuse Enhances Pulmonary Edema in Acute Respiratory Distress Syndrome. Alcohol Clin Exp Res 2009; 33(10): 1-7.

Martin G, Brunkhorst FM, Janes J, Reinhart K, Sundin DP, Garnett K, Beale R. The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes. Crit Care 2009; 13(3): R103.

Jeng L, Yamshchikov AV, Judd SE, Blumberg HM, Martin GS, Ziegler TR, Tangpricha V. Alterations in vitamin D status and blood anti-microbial peptide levels in patients in the intensive care unit with sepsis. J Transl Med 2009, 7:28.

Erickson SE, Martin GS, Davis JL, Matthay MA, Eisner MD. Recent Trends in Acute Lung Injury Mortality: 1996-2005. Crit Care Med 2009; 37(5):1574-9.

Esper AM, Moss M, Martin GS. The effect of diabetes mellitus on organ dysfunction in sepsis. Crit Care 2009: 13(1): R18.

Erickson SE, Shlipak MG, Martin GS, Wheeler AP, Ancukiewicz M, Matthay M, Eisner MD. Racial and ethnic disparities in mortality from acute lung injury. Crit Care Med 2009; 37(1): 1-6.

Wurfel MM, Gordon AC, Holden TD, Radella F, Strout J, Kajikawa O, Ruzinski JT, Rona G, Black A, Stratton S, Jarvik GP, Hajjar AM, Nickerson DA, Rieder M, Sevransky J, Maloney JP, Moss M, Martin G, Shanholtz C, Garcia JGN, Gao L, Brower R, Barnes KC, Walley KR, Russell JA, Martin TR. Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis. Am J Respir Crit Care Med 2008; 178(7): 710-20.

Sevransky JE, Martin GS, Mendez-Tellez P, Shanholtz C, Brower R, Pronovost PJ, Needham DM. Pulmonary versus Non-Pulmonary Sepsis and Mortality in Acute Lung Injury. Chest 2008; 134(3): 534-538.

Berkowitz DM, Danai PA, Eaton S, Moss M, Martin GS. Accurate characterization of extravascular lung water in acute respiratory distress syndrome. Crit Care Med 2008; 36(6): 1803-09.

Danai PA, Sinha S, Moss M, Haber MJ, Martin GS. Seasonal Variation in the Epidemiology of Sepsis. Crit Care Med 2007; 35(2):410-15.

O’Brien JM, Lu B, Ali NA, Martin GS, Aberegg SK, Marsh CB, Lemeshow S, Douglas IS. Alcohol dependence is independently associated with sepsis, septic shock and hospital mortality among adult intensive care unit patients. Crit Care Med 2007; 35(2): 345-50.

Slynkova K, Mannino DM, Martin GS, Morehead RS, Doherty DE. The role of body mass index and diabetes in the development of critical illness and subsequent mortality. Crit Care 2006; 10(5): R137.

Esper AM, Moss M, Lewis CA, Nisbet R, Mannino DM, Martin GS. The role of infection and co-morbidity: factors that influence disparities in sepsis. Crit Care Med 2006; 34(10): 2576-82.

Danai PA, Mannino DM, Moss M, Martin GS. The epidemiology of sepsis among patients with cancer. Chest; 2006: 129(6): 1432-40.

Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Crit Care Med 2006; 34(1): 15-21.

Silverboard H, Aisiku I, Martin GS, Adams MR, Rozycki G, Moss M. The role of acute blood transfusion in the development of acute respiratory distress syndrome in patients with severe trauma. J Trauma 2005; 59(3): 717-23.

Martin GS, Moss M, Wheeler AP, Mealer M, Morris JA, Bernard GR. A randomized controlled trial of furosemide with or without albumin in hypoproteinemic acute lung injury patients. Crit Care Med 2005; 33(8): 1681-87.

Martin GS, Eaton S, Mealer M, Moss M. Extravascular lung water in patients with severe sepsis: a prospective cohort study. Crit Care 2005; 9: R74-82.

Quinlan GJ, Mumby S, Martin GS, Bernard GR, Gutteridge JMC, Evans TW. Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury. Crit Care Med; 2004; 32(3): 755-59.

Martin GS, Mannino DM, Eaton S, Moss M. The Epidemiology of Sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348(16): 1546-54.

Martin GS, Ely EW, Carroll FE, Bernard GR. Findings on the portable chest radiograph correlate with fluid balance in critically ill patients. Chest 2002; 122(6): 2087-95.

Martin GS, Mangialardi RJ, Wheeler AP, Dupont WD, Morris JA, Bernard GR. A randomized controlled clinical trial of albumin and furosemide therapy in hypoproteinemic patients with acute lung injury. Crit Care Med 2002; 30(10): 2175-82.

Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD, Higgins SB, Swindell BB, and the Ibuprofen in Sepsis investigators. Hypoproteinemia predicts ARDS, weight gain, and death in patients with sepsis. Crit Care Med 2000, 28(9): 3137-45.

Martin GS, Becker BN, Schulman G. Cardiac troponin-I accurately predicts myocardial injury in renal failure. Nephrol Dial Transplant 1998; 13: 1709-12.