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Dr. Brian Zanoni

Dr. Brian Zanoni, MD, MPH

Dr. Brian Zanoni completed a combined residency in Internal Medicine and Pediatrics at Baylor College of Medicine. He then worked in Botswana and South Africa from 2006 to 2012 treating both adults and children living with HIV and tuberculosis, conducting pediatric HIV outcomes research, and training local staff in HIV management. While living in South Africa, he founded the Teen Clinic at Don McKenzie Hospital and the non-profit organization, Umndeni Care Program which focuses on in-home HIV and TB testing and linkage to care in rural KwaZulu-Natal, South Africa.

He completed Infectious Disease and HIV fellowships at Massachusetts General Hospital and Brigham and Woman’s Hospital and earned an MPH from Harvard T.H. Chan School of Public Health. His research focuses on transition care for adolescents living with HIV in South Africa.

He is an Assistant Professor in Medicine and Pediatric Infectious Diseases at Emory University and is the deputy medical director of the Ponce Family and Youth Clinic. In addition to research, Dr. Zanoni sees adult and pediatric patients at the Ponce IDP Clinic and attends on the HIV inpatient service at Grady Memorial Hospital.


  • Pediatric Infectious Diseases


  • Emory

Education & Training

  • Medical School: Georgetown University School of Medicine
  • Residency: Baylor College of Medicine


Zanoni BC. Phungula, T. Zanoni, H. France, H. Feeney, M. Impact of Tuberculosis Cotreatment on Viral Suppression Rates Among HIV-positive Children Initiating HAART. AIDS. 2011 Jan 2;25(1):49-55. PMID: 20935555.

Zanoni BC, Phungula T, Zanoni HM, France H, Feeney ME Risk Factors Associated with Increased Mortality among HIV Infected Children Initiating Antiretroviral Therapy (ART) in South Africa. 2011 PloS one 6: e22706.

Ruel TD, Zanoni BC, Ssewanyana I, Cao H, Havlir DV, et al. (2011) Sex Differences in HIV RNA Level and CD4 Cell Percentage During Childhood. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 53: 592-599.

Zanoni, BC. Phungula, T. Zanoni, H. France, H. Feeney, M. Predictors of Poor CD4 and Weight Recovery in HIV-infected Children Initiating ART in South Africa. PLoS One 7(3): e33611. doi:10.1371/journal.pone.0033611.

Zanoni, BC. Sunpath, H. Feeney, M. Pediatric Response to Second-line Antiretroviral Therapy. PLoS One 2012;7(11):e49591. doi: 10.1371/journal.pone.0049591.

Mayer, KH. Zanoni, BC. HIV Chemoprophylaxis for Adolescents: Educable Moment, Not Magic Bullet. Clinical Infectious Diseases 2013 Apr;56(8):1156-8.

Zanoni, BC. Mayer, KH. The Adolescent and Young Adult HIV Cascade of Care in the United States: Exaggerated Health Disparities. AIDS Patient Care STDS 2014 Mar;28(3): 128-35.

Zanoni, BC. Gandhi, R. Update on Opportunistic Infections in the Era of Effective Antiretroviral Therapy. Infectious Disease Clinics of North America 2014;(28): 501 - 518.

Georgette N, Siedner MJ, Zanoni BC, Sibaya T, Petty CR, Carpenter S, Haberer JE. The Acceptability and Perceived Usefulness of a Weekly Clinical SMS Program to Promote HIV Antiretroviral Medication Adherence in KwaZulu-Natal, South Africa. AIDS Behav. 2016;20(11):2629-38.

Zanoni BC, Archary M, Buchan S, Katz I, Haberer J. Systematic Review and Meta-analysis of the Adolescent HIV Continuum of Care in South Africa: The Cresting Wave. BMJ Global Health. October 24, 2016 1 (3) e000004; Doi: 10.1136/bmjgh-2015-000004.

Georgette N, Siedner MJ, Petty CR, Zanoni BC, Carpenter S, Haberer JE. Impact of a clinical program using weekly Short Message Service (SMS) on antiretroviral therapy adherence support in South Africa: a retrospective cohort study. BMC Med Inform Decis Mak. 2017;17(1):18.

Boerma, R. S., T. Bunupuradah, D. Dow, J. Fokam, A. Kariminia, D. Lehman, C. Kityo, V. Musiime, P. Palumbo, A. Schoffelen, S. Sophan, B. Zanoni, T. F. Rinke de Wit, J. C. J. Calis, K. C. E. Sigaloff and G. Paediatric Second-line Study Multicentre analysis of second-line antiretroviral treatment in HIV-infected children: adolescents at high risk of failure. Journal of the International AIDS Society 2017 20(1): 21930.

Zanoni BC, Sibaya T, Cairns C, Lammert S, Haberer JE. Higher retention and viral suppression with adolescent-focused HIV clinic in South Africa. PLoS One. 2017;12(12):e0190260.

Zanoni BC, Elliott RJ, Neilan AM, Haberer JE. Screening for HIV and linkage to care in adolescents: insights from a systematic review of recent intervention in high versus low and middle-income settings. Adolescent Health, Medicine and Therapeutics. 2018 Dec 4; 9:211-235.

Zanoni BC, Sibaya T, Cairns C, Haberer JE. Barriers to Retention in Care are Overcome by Adolescent-Friendly Services for Adolescents Living with HIV in South Africa: A Qualitative Analysis AIDS and Behavior 2019;23(4):957-65 DOI: 10.1007/s10461-0018-2352-6.

Kemigisha E, Zanoni BC, Bruce K, Menjivar R, Kadengye D, Atwine D, Rukundo GZ. Prevalence of depressive symptoms and associated factors among adolescents living with HIV/AIDS in South Western Uganda. AIDS Care. 2019 Jan 8:1-7.

Zanoni BC, Haberer JE. The meaning of "rapid" antiretroviral therapy initiation for adolescents with HIV in sub-Saharan Africa. J Infect Dis. 2020 Aug 4; 222(5) 705-707.

Archary M, Zanoni BC, Lallemant M, Suwannaprom P, Clarke D, Penazzato M. Acceptability and Feasibility of Using Raltegravir Oral Granules for the Treatment of Neonates in a Low-resource Setting. Pediatr Infect Dis J. 2020;39(1):57-60.

Zanoni BC, Archary M, Sibaya T, Musinguzi N, Haberer JE Transition from Pediatric to Adult Care for Adolescents Living with HIV in South Africa: A Natural Experiment and Survival Analysis. PLoS One. 2020 Oct 27; 15(10):e0240918.

Zanoni BC, Archary M, Subramoney T, Sibaya T, Psaros C, Haberer JE. Disclosure, Social support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV infected Adolescents: A Qualitative Dyadic Analysis. AIDS and Behavior. 2021;25(1):237-248 Doi: 10.1007/s10461-020-02968-1.

Zanoni BC, Archary M, Subramoney T, Sibaya T, Psaros C, Haberer JE. "It was not okay because you leave your friends behind": A prospective analysis of transition to adult care for adolescents living with perinatally-acquired HIV in South Africa. Vulnerable Children and Youth Studies, 2021;16(3):206-20 Doi: 10.1080/17450128.2021.1876965.

Zanoni BC, Archary M, Sibaya T, Msunguzi N, Haberer JE. Development and Validation of the HIV Adolescent Readiness to Transition Scale (HARTS). Journal of the International AIDS Society 2021;24(7):e25767.

Nkosi B, Zanoni BC, Strode A, Seeley J. The Ethical-Legal Requirements for Adolescent Self-consent to Research in Sub-Saharan Africa: A Scoping Review. Bioethics. Accepted for publication 2021.

Dube-Pule A, Zanoni BC, Connolly C, Shabangu M, Archary M. Evaluation of an SMS-based mHealth intervention to enhance early infant diagnosis follow-up testing and assessment of postnatal prophylaxis. Southern African Journal of HIV Medicine 2021;22(1):a1301.

Zanoni BC, Archary M, Sibaya T, Goldstain M, Bergam S, Denton D, Cordero V, Peng C, Psaros C, Marconi VC, Haberer JE. Mobile Phone-Based Intervention Among Adolescents Living With Perinatally Acquired HIV Transitioning from Pediatric to Adult Care: Protocol for the Interactive Transition Support for Adolescents Living With HIV using Social Media (InTSHA) Study. JMIR Res Protoc. 2022;11(1):e35455. doi:10.2196/35455.