Ponce De Leon Center Change Location

Photo of Ponce de Leon Health Center building

Welcome to our Ponce De Leon Center

The Ponce De Leon Center is one of the largest, most comprehensive facilities dedicated to the treatment of advanced HIV/AIDS in the United States. Founded in 1986, the Ponce Center and its onsite affiliates provide various medical and support services to approximately 5000 eligible men, women, adolescents, and children living with HIV/AIDS.

The Ponce Center integrates primary internal medicine and Infectious Disease subspecialty care in the Main, Family, and Transition Clinics. Staffed by doctors, nurse practitioners and physician assistants, nurses, and more than 100 interagency staff. Our care teams seamlessly provide onsite medical, support, and community services.

To qualify for care in the Ponce Center, adult referrals must have a previous AIDS diagnosis and/or a Nadir CD4 count below 200. Pediatric and adolescent patients have no such restrictions.

Access to Care

Accessing Grady’s Ponce De Leon Center is simple. We treat individuals who have been diagnosed with HIV. Our services are available to all individuals 25 or younger, regardless of CD4 count or county of residence. Individuals diagnosed with HIV who are over 25 must reside in the 20-county Atlanta Eligible Metropolitan Area and have a CD4 count of less than 200 or an AIDS defining illness, be a pregnant woman, be a Grady patient, or meet other criteria.

If you are HIV+ and are interested in receiving care at Grady, please call (404) 616-2440 to find out if you are eligible to become a patient.

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Location & Directions

Ponce De Leon Center
341 Ponce De Leon Ave. NE
Atlanta, GA 30308

Monday - Friday: 8 AM - 5 PM
Extended hours on Thursday

(404) 616-2440 (Main)
(404) 616-1000 (Appointments)

Parking is available

Public Transportation

  • Buses: 2, 99, 102

Need directions? Download Grady GO! our free app for turn-by-turn directions to your destination.

Download our app from the Apple Store   Download our app from Google Play

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If You are Sick

If you are sick and need to see the doctor, call the center at (404) 616-2440. A nurse may ask you a few questions that will help them decide how soon you need to be seen.

If you are a Grady patient and need help deciding if you should see a doctor, assistance is just a phone call away. Grady’s Advice Nurse Line is available 24 hours a day, seven days a week. Staffed by specially trained registered nurses and on-call physicians, the Advice Nurse Line can help guide you during times of worry and uncertainty. We’re here for you, give us a call at (404) 616-0600.

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What We Treat

One of the largest and most comprehensive HIV treatment programs in the nation, the Ponce Center provides care for more than 5,000 thousand men, women, and children. The center partners with many local AIDS service organizations – some housed onsite – to meet the complex needs of patients. The 90,000 square-foot facility offers an extensive range of outpatient and community based services. Learn more about our Infectious Disease Program.

Also at this location:

  • Dental
  • ECHO
  • Infusion



  • Imaging
  • Lab
  • Pharmacy
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The pharmacy at the Ponce Center is open Monday – Friday from 9 AM – 5 PM.

If you need a prescription refill, call (404) 616-5500 and follow the prompts. You will need the 9-digit number on the bottom left corner of your prescription label.

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Our Doctors

Every hospital treats patients. At Grady, we strive to treat them better, more efficiently, and more effectively. Our mission to care for all who need us attracts HIV/AIDS specialists from across the nation. They are drawn here by the knowledge that we test the limits of medicine by innovating existing standards of care, researching cutting-edge drugs and therapies, and exploring novel treatments.

Our zeal for innovation has given Grady a national reputation for medical advancement in areas like HIV/AIDS, heart disease, cancer, burn, stroke, diabetes, infectious diseases, women’s health, sickle cell, and other conditions cared for by specialists in our centers of excellence. Access to all of these accredited practices is available to every Grady patient and our collegial environment means that specialists routinely help to care for their colleagues’ patients.

Though clinicians are drawn by Grady’s reputation, most are employed by the Emory and Morehouse schools of medicine, which staff our medical services. Grady is one of a handful of U.S. health systems.